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Ethics declarations Ethics approval and consent to participate The study has been appraised and approved by the Research Ethics Approvals Committee (REAC) with Reference number EA02180123

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Franois Grimault, an apprentice working under the aforementioned French pharmacist Franois Dorvault (author of the pharmacopeia, LOfficine), and investor Francisque-Jean-Baptiste Rigaud formed the company in 1853 after purchasing majority shares in Dorvaults Parisian pharmaceutical practice